This is a synthetic peptide designed for use in combination with anti-MED21 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
MED21
(Mediator Complex Subunit 21 (MED21))
Hintergrund
The Mediator is a multiprotein coactivator that is required by DNA-binding transcription factors for transcriptional activation of polymerase II-transcribed genes. MED21 is a Mediator subunit predicted to reside in the middle module and appears to be a core subunit found in nearly all Mediator preparations.
Alias Symbols: SRB7, SURB7
Protein Interaction Partner: CDKN1A,TFF1,THRA,THRB,BRCA1,BTF3,CDK8,CDK9,POLR2A,TCEB3,TFG,THRA,THRB,BRCA1,CDK7,CDK8,CREBBP,ESR1,ESR2,GTF2B,GTF2E1,GTF2F1,GTF2H4,HNF4A,KAT2B,MED1,MED10,MED12,MED14,MED18,MED19,MED26,MED28,MED29,MED30,MED6,MED9,PCBD2,POLR2A,PPARGC1A,SMARCB1,SREBF1,TARBP2,