This is a synthetic peptide designed for use in combination with anti-MAX antibody (Catalog #: ARP38145_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
MAX
Reaktivität: Human, Maus, Ratte
Wirt: Synthetic
BP, BI
Applikationshinweise
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
MAX
(MYC Associated Factor X (MAX))
Synonyme
CG9648 Peptide, Dmel\\CG9648 Peptide, MAX Peptide, bHLHd9 Peptide, dMax Peptide, dmax Peptide, max Peptide, bhlhd4 Peptide, bhlhd5 Peptide, bhlhd6 Peptide, bhlhd7 Peptide, bhlhd8 Peptide, xmax2 Peptide, xmax4 Peptide, xmax Peptide, AA960152 Peptide, AI875693 Peptide, bHLHd4 Peptide, bHLHd5 Peptide, bHLHd6 Peptide, bHLHd7 Peptide, bHLHd8 Peptide, fa92b04 Peptide, fb52a04 Peptide, fb95h11 Peptide, wu:fa92b04 Peptide, wu:fb52a04 Peptide, wu:fb95h11 Peptide, zmax Peptide, CG9648 gene product from transcript CG9648-RD Peptide, MYC associated factor X L homeolog Peptide, MYC associated factor X Peptide, Max protein Peptide, MYC associated factor X S homeolog Peptide, myc associated factor X Peptide, Max Peptide, max.L Peptide, MAX Peptide, max Peptide, max.S Peptide
Hintergrund
MAX is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation.The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Multiple alternatively spliced transcript variants have been described for this gene but the full length nature for some of them is unknown.
Alias Symbols: orf1, bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8
Protein Interaction Partner: MSH2,MXD1,MXI1,MYC,CASP5,CASP7,CSNK2A1,EPAS1,HIF1A,MAD1L1,MAPK14,MAX,MNT,MSH2,MXD1,MXD3,MXD4,MYC,MYCL1,MYCN,PLEKHF2,SMAD3,SMAD4,SNIP1,SPAG9,TEAD1,TRRAP,EP400,KAT2A,KDM5C,MAD1L1,MAX,MNT,MSH2,MXD1,MXD3,MXD4,MXI1,MYC,MYCL1,MYCN,PLEKHF2,SMAD3,SMAD4,SPAG9,TEAD1,TRRAP,ZBTB17