Mannan-Binding Lectin Serine Peptidase 1 (MASP1) (N-Term) Peptid
MASP1
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN979837
Kurzübersicht für Mannan-Binding Lectin Serine Peptidase 1 (MASP1) (N-Term) Peptid (ABIN979837)
Target
MASP1
(Mannan-Binding Lectin Serine Peptidase 1 (MASP1))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- N-Term
-
Sequenz
- PGSFMSITFR SDFSNEERFT GFDAHYMAVD VDECKEREDE ELSCDHYCHN
-
Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-MASP1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Aufreinigung
- Purified
-
-
-
-
Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Konzentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handhabung
- Avoid repeated freeze-thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- MASP1 (Mannan-Binding Lectin Serine Peptidase 1 (MASP1))
-
Hintergrund
-
This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway.
Alias Symbols: CRARF, CRARF1, DKFZp686I01199, FLJ26383, MASP, MGC126283, MGC126284, PRSS5, RaRF
Protein Size: 699 -
Molekulargewicht
- 28 kDa
-
Gen-ID
- 5648
-
NCBI Accession
- NM_001879, NP_001870
-
UniProt
- P48740
Target
-
Sie sind hier:
