Mitogen-Activated Protein Kinase 1 (MAPK1) (Middle Region) Peptid
MAPK1
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN979791
Kurzübersicht für Mitogen-Activated Protein Kinase 1 (MAPK1) (Middle Region) Peptid (ABIN979791)
Target
ERK2 (MAPK1)
(Mitogen-Activated Protein Kinase 1 (MAPK1))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- RDLKPSNLLL NTTCDLKICD FGLARVADPD HDHTGFLTEY VATRWYRAPE
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-MAPK1 Antibody(ARP58900_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ERK2 (MAPK1) (Mitogen-Activated Protein Kinase 1 (MAPK1))
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Hintergrund
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The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
Alias Symbols: ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk
Protein Interaction Partner: DAPK1,MAP3K1,MBP,RAF1,RPS6KA2,TNIP1,TSC2,VAV1,MAP2K1,MAP2K2,AR,ARRB1,ARRB2,BCL2,BCL6,BRAF,C1QBP,CAD,CALCOCO1,CASP8,CASP9,CAV1,CD19,CDX2,CEBPB,CEP55,CMTM3,CSDA,DAPK1,DUSP1,DUSP16,DUSP2,DUSP3,DUSP4,DUSP5,DUSP6,DUSP7,DUSP9,DYRK1B,EGFR,EIF4EBP1,ELK1,EPOR,ERF,
Protein Size: 360 -
Molekulargewicht
- 41 kDa
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Gen-ID
- 5594
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NCBI Accession
- NM_138957, NP_620407
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UniProt
- P28482
Target
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