Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14) (N-Term) Peptid
MAP3K14
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN979775
Kurzübersicht für Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14) (N-Term) Peptid (ABIN979775)
Target
MAP3K14
(Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequenz
- SEAGPAAISI IAQAECENSQ EFSPTFSERI FIAGSKQYSQ SESLDQIPNN
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-MAP3K14 Antibody(ARP42161_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14))
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Hintergrund
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This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor.
Alias Symbols: FTDCR1B, HS, HSNIK, NIK
Protein Interaction Partner: CHUK,IKBKAP,IKBKB,TRAF1,TRAF2,TRAF3,TRAF5,TRAF6,ALPL,CASP8,CDC37,CHUK,EDAR,EGFR,FBL,GRB10,GRB14,GRB7,HSP90AA1,HSP90AB1,IKBKAP,IKBKB,IKBKG,MAP2K4,MAP3K14,MAP3K7,MAP3K8,MAPK3,NFKB2,PEBP1,PELI3,RIPK1,RPL30,RPL4,RPL5,RPL6,RPS11,RPS13,TRAF1,TRAF2,TRAF3,TRAF5,T
Protein Size: 947 -
Molekulargewicht
- 104 kDa
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Gen-ID
- 9020
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NCBI Accession
- NM_003954, NP_003945
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UniProt
- Q99558
Target
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