V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF) (N-Term) Peptid
MAF
Reaktivität: Human
Wirt: Synthetic
BP, WB, IHC
Produktnummer ABIN979702
150,78 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach:
Deutschland
Lieferung in 15 bis 22 Werktagen
Kurzübersicht für V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF) (N-Term) Peptid (ABIN979702)
Target
MAF
(V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein Region
- N-Term
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-MAF antibody (Catalog #: ARP38607_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MAF (V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))
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Hintergrund
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MAF acts as a transcriptional activator or repressor. It is involved in embryonic lens fiber cell development. It recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. MAF is also involved in the initial chondrocyte terminal differentiation and the disappearance of hypertrophic chondrocytes during endochondral bone development. When overexpressed, MAF represses anti-oxidant reponse element (ARE)-mediated transcription. It may be involved either as an oncogene or as a tumor suppressor, depending on the cell context.
Alias Symbols: MGC71685, c-MAF
Protein Interaction Partner: CREBBP,EP300,CREBBP,EP300,ETS1,FOS,JUN,MAF,MAFA,MAFG,MYB,SMARCA5,SOX9,USF2,CREBBP,EP300,ETS1,HOXD12,MAF,MAFG,MYB,SOX9,USF2
Protein Size: 373 -
Molekulargewicht
- 38 kDa
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Gen-ID
- 4094
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NCBI Accession
- NM_001031804, NP_001026974
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UniProt
- O75444
Target
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