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Lymphotoxin beta (TNF Superfamily, Member 3) (LTB) (N-Term) Peptid

LTB Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN979642
  • Target Alle LTB Produkte
    LTB (Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))
    Protein Region
    N-Term
    Spezies
    Human
    Quelle
    • 3
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    AVPITVLAVL ALVPQDQGGL VTETADPGAQ AQQGLGFQKL PEEEPETDLS
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-LTB Antibody(ARP45280_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    LTB (Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))
    Synonyme
    AI662801 Peptide, LTbeta Peptide, Tnfc Peptide, Tnfsf3 Peptide, p33 Peptide, TNFC Peptide, TNFSF3 Peptide, LT-b Peptide, LT-beta Peptide, TNF-C Peptide, lymphotoxin B Peptide, lymphotoxin beta Peptide, Ltb Peptide, LTB Peptide
    Hintergrund
    Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 Molecule alpha/2 Molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms.

    Alias Symbols: TNFC, TNFSF3, p33

    Protein Interaction Partner: LTA,LTB,LTBR,TNFRSF1A,TNFSF14,LTA,TNFRSF1A

    Protein Size: 244
    Molekulargewicht
    25 kDa
    Gen-ID
    4050
    NCBI Accession
    NM_002341, NP_002332
    UniProt
    Q06643
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