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Lamin B1 (LMNB1) (Middle Region) Peptid

LMNB1 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN979358

Kurzübersicht für Lamin B1 (LMNB1) (Middle Region) Peptid (ABIN979358)

Target

Lamin B1 (LMNB1)

Spezies

Human

Quelle

  • 7
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-LMNB1 antibody (Catalog #: ARP46137_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    Lamin B1 (LMNB1)

    Hintergrund

    LAMNB1 encodes for one of the two B type proteins of the nuclear lamina, B1. The Vertebrate lamins consist of two types, A and B. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression.The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: ADLD, LMN, LMN2, LMNB, MGC111419

    Protein Interaction Partner: LMNA,LMNA,LMNA,LMNB1,URB2,CASP3,CASP6,CDK1,GZMA,GZMB,LBR,LMNA,MELK,PLEC,PRKCA,PRKCB,PRKCD,PRPH,SUMO4,TMPO,TOR1AIP1,URB2,AIRE,EMD,LMNA,MCM10,NDEL1,PRKCA,PRKCB,SMARCA4,SPTAN1,TMPO,VIM

    Protein Size: 586

    Molekulargewicht

    66 kDa

    Gen-ID

    4001

    NCBI Accession

    NM_005573, NP_005564

    UniProt

    P20700
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