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Leukemia Inhibitory Factor (LIF) Peptid

LIF Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN979312
  • Target Alle LIF Produkte
    LIF (Leukemia Inhibitory Factor (LIF))
    Spezies
    Human
    Quelle
    • 6
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-LIF antibody (Catalog #: ARP54690_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    LIF (Leukemia Inhibitory Factor (LIF))
    Synonyme
    CDF Peptide, DIA Peptide, HILDA Peptide, MLPLI Peptide, LIF, interleukin 6 family cytokine Peptide, leukemia inhibitory factor Peptide, LIF Peptide, Lif Peptide
    Hintergrund
    LIF is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface.Leukaemia inhibitory factor is a cytokine that induces macrophage differentiation. Neurotransmitters and neuropeptides, well known for their role in the communication between neurons, are also capable of activating monocytes and macrophages and inducing chemotaxis in immune cells. LIF signals through different receptors and transcription factors. LIF in conjunction with BMP2 acts in synergy on primary fetal neural progenitor cells to induce astrocytes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: CDF, D-FACTOR, HILDA, DIA

    Protein Interaction Partner: IL6ST,LIFR,LIFR

    Protein Size: 202
    Molekulargewicht
    22 kDa
    Gen-ID
    3976
    NCBI Accession
    NM_002309, NP_002300
    UniProt
    P15018
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