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Leukemia Inhibitory Factor (LIF) Peptid

LIF Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN979312

Kurzübersicht für Leukemia Inhibitory Factor (LIF) Peptid (ABIN979312)

Target

LIF (Leukemia Inhibitory Factor (LIF))

Spezies

Human

Quelle

  • 6
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-LIF antibody (Catalog #: ARP54690_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    LIF (Leukemia Inhibitory Factor (LIF))

    Hintergrund

    LIF is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface.Leukaemia inhibitory factor is a cytokine that induces macrophage differentiation. Neurotransmitters and neuropeptides, well known for their role in the communication between neurons, are also capable of activating monocytes and macrophages and inducing chemotaxis in immune cells. LIF signals through different receptors and transcription factors. LIF in conjunction with BMP2 acts in synergy on primary fetal neural progenitor cells to induce astrocytes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: CDF, D-FACTOR, HILDA, DIA

    Protein Interaction Partner: IL6ST,LIFR,LIFR

    Protein Size: 202

    Molekulargewicht

    22 kDa

    Gen-ID

    3976

    NCBI Accession

    NM_002309, NP_002300

    UniProt

    P15018
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