Lamin B Receptor (LBR) (Middle Region) Peptid
LBR
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle Lamin B Receptor (LBR) Produkte
- Lamin B Receptor (LBR)
- Protein Region
- Middle Region
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- GANSQKNAFR KNPSDPKLAH LKTIHTSTGK NLLVSGWWGF VRHPNYLGDL
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-LBR Antibody(ARP45263_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Lamin B Receptor (LBR)
- Hintergrund
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The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.
Alias Symbols: DHCR14B, LMN2R, MGC9041, PHA
Protein Interaction Partner: AKAP8L,CBX3,CBX5,FNBP4,LBR,LMNB1,PRM1,SRPK1,YWHAG,AKAP8L,CBX3,CBX5,FNBP4,MECP2,YWHAG,tat
Protein Size: 615 - Molekulargewicht
- 71 kDa
- Gen-ID
- 3930
- NCBI Accession
- NM_002296, NP_002287
- UniProt
- Q14739
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