Kringle Containing Transmembrane Protein 1 (KREMEN1) (N-Term) Peptid
KREMEN1
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN979110
Kurzübersicht für Kringle Containing Transmembrane Protein 1 (KREMEN1) (N-Term) Peptid (ABIN979110)
Target
KREMEN1
(Kringle Containing Transmembrane Protein 1 (KREMEN1))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-KREMEN1 antibody (Catalog #: ARP44879_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))
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Hintergrund
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KREMEN1 is a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. It is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.
Alias Symbols: FLJ31863, KREMEM1, KREMEN, KRM1
Protein Interaction Partner: DKK1
Protein Size: 475 -
Molekulargewicht
- 50 kDa
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Gen-ID
- 83999
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NCBI Accession
- NM_001039570, NP_001034659
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UniProt
- C1P671
Target
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