Karyopherin (Importin) beta 1 (KPNB1) (N-Term) Peptid
KPNB1
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle KPNB1 Produkte
- KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))
- Protein Region
- N-Term
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- EHMKESTLEA IGYICQDIDP EQLQDKSNEI LTAIIQGMRK EEPSNNVKLA
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-KPNB1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))
- Synonyme
- Afu1g15720 Peptide, AO090005001133 Peptide, imb1 Peptide, impnb Peptide, ipo1 Peptide, ipob Peptide, ntf97 Peptide, IMB1 Peptide, IPO1 Peptide, IPOB Peptide, Impnb Peptide, NTF97 Peptide, AA409963 Peptide, importin beta-1 subunit Peptide, Importin beta-1 subunit Peptide, karyopherin (importin) beta 1 L homeolog Peptide, importin beta 1 Peptide, karyopherin subunit beta 1 Peptide, karyopherin (importin) beta 1 Peptide, AFUA_1G15720 Peptide, AOR_1_1974174 Peptide, Bm1_57540 Peptide, PMAA_065830 Peptide, AFLA_083750 Peptide, TSTA_085870 Peptide, BDBG_07509 Peptide, MCYG_00039 Peptide, kpnb1.L Peptide, LOC100533387 Peptide, KPNB1 Peptide, Kpnb1 Peptide
- Hintergrund
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Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.
Alias Symbols: IMB1, IPO1, IPOB, Impnb, MGC2155, MGC2156, MGC2157, NTF97
Protein Interaction Partner: CD99,RAN,SOX9,rev,tat,CD99,CHD3,CSE1L,CSNK1A1,ELAVL1,FGFR1,H1F0,IGFBP3,IGFBP5,IPO7,IPO8,KPNA2,KPNA3,KPNA6,KPNB1,LYST,NFYA,NUP153,NUP50,NUP62,NUP98,PIAS4,PLCD1,PRKD3,PTHLH,PTMA,PTN,PTPN2,RAN,RANBP2,RPL5,RUNX1T1,SMAD2,SMAD3,SMN2,SMNDC1,SNUPN,SOX9,SREBF2,TER
Protein Size: 876 - Molekulargewicht
- 96 kDa
- Gen-ID
- 3837
- NCBI Accession
- NM_002265, NP_002256
- UniProt
- Q14974
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