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Karyopherin alpha 6 (Importin alpha 7) (KPNA6) Peptid

KPNA6 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN979104
  • Target Alle KPNA6 Produkte
    KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))
    Spezies
    Human
    Quelle
    • 3
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-KPNA6 antibody (Catalog #: ARP54879_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))
    Synonyme
    IPOA7 Peptide, Kpna5 Peptide, NPI-2 Peptide, KPNA7 Peptide, karyopherin subunit alpha 6 Peptide, karyopherin (importin) alpha 6 Peptide, karyopherin alpha 6 (importin alpha 7) Peptide, karyopherin alpha 6 (importin alpha 7) S homeolog Peptide, KPNA6 Peptide, Kpna6 Peptide, kpna6.S Peptide
    Hintergrund
    The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. KPNA6 is a member of the importin alpha family.Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: FLJ11249, IPOA7, KPNA7, MGC17918

    Protein Interaction Partner: ANP32A,BRCA1,CSE1L,KPNB1,RELB,STAT1,STAT3,TAF9,KPNB1,MEPCE,RELB,SPOP

    Protein Size: 536
    Molekulargewicht
    60 kDa
    Gen-ID
    23633
    NCBI Accession
    NM_012316, NP_036448
    UniProt
    O60684
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