This is a synthetic peptide designed for use in combination with anti-KNG1 antibody (Catalog #: ARP45680_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Kininogens are inhibitors of thiol proteases. HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII and inhibits the thrombin- and plasmin-induced aggregation of thrombocytes. The active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects such as influence in smooth muscle contraction, induction of hypotension, natriuresis and diuresis, etc.
Alias Symbols: BDK, KNG
Protein Interaction Partner: AGT,APP,CAPN1,CAPN2,CD93,CPN1,CTSG,CTSK,CTSL1,CTSS,ELANE,F11,F2,FTL,GP1BA,HABP2,ITGB2,KLK1,KLKB1,KNG1,KRT1,MEP1A,PLAUR,PLG,PREP,RXFP4,THBS1,VTN,CD93,ELANE,F11,FTL,ITGB2,KLKB1,KRT1,PLAUR,PLG,VTN