This is a synthetic peptide designed for use in combination with anti-KNG1 antibody (Catalog #: ARP45680_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
KNG1
(Kininogen 1 (KNG1))
Hintergrund
Kininogens are inhibitors of thiol proteases. HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII and inhibits the thrombin- and plasmin-induced aggregation of thrombocytes. The active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects such as influence in smooth muscle contraction, induction of hypotension, natriuresis and diuresis, etc.
Alias Symbols: BDK, KNG
Protein Interaction Partner: AGT,APP,CAPN1,CAPN2,CD93,CPN1,CTSG,CTSK,CTSL1,CTSS,ELANE,F11,F2,FTL,GP1BA,HABP2,ITGB2,KLK1,KLKB1,KNG1,KRT1,MEP1A,PLAUR,PLG,PREP,RXFP4,THBS1,VTN,CD93,ELANE,F11,FTL,ITGB2,KLKB1,KRT1,PLAUR,PLG,VTN