Klotho (KL) (N-Term) Peptid
KL
Reaktivität: Maus
Wirt: Synthetic
BP, WB
Produktnummer ABIN978987
Kurzübersicht für Klotho (KL) (N-Term) Peptid (ABIN978987)
Target
Klotho (KL)
Spezies
Maus
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequenz
- GAAPSDSPIV VAPSGAPSPP LSSTGDVASD SYNNVYRDTE GLRELGVTHY
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-Kl Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Klotho (KL)
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Hintergrund
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Kl may have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 241 and 874, suggesting it may be inactive as a glycosidase in vivo. It may be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D. Essential factor for the specific interaction between FGF23 and FGFR1.
Alias Symbols: alpha-kl
Protein Size: 1014 -
Molekulargewicht
- 116 kDa
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Gen-ID
- 16591
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NCBI Accession
- NM_013823, NP_038851
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UniProt
- O35082
Target
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