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Kinesin Associated Protein 3 (KIFAP3) (Middle Region) Peptid

KIFAP3 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN978973
150,78 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach: Deutschland
Lieferung in 15 bis 22 Werktagen

Kurzübersicht für Kinesin Associated Protein 3 (KIFAP3) (Middle Region) Peptid (ABIN978973)

Target

KIFAP3 (Kinesin Associated Protein 3 (KIFAP3))

Spezies

Human

Quelle

  • 4
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Sequenz

    WLEMVESRQM DESEQYLYGD DRIEPYIHEG DILERPDLFY NSDGLIASEG

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-KIFAP3 Antibody(ARP55128_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    KIFAP3 (Kinesin Associated Protein 3 (KIFAP3))

    Hintergrund

    The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras, one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein.

    Alias Symbols: FLJ22818, KAP3, SMAP, Smg-GDS, dJ190I16.1, KAP-3

    Protein Interaction Partner: APC,KIF3B,KIFAP3,MAP3K10,MINK1,RAP1GDS1,RBFOX1,RPGR,SMC3,SRC,APC,AR,MAP3K10,MAP3K11,RAP1GDS1,SMC3,SRC

    Protein Size: 792

    Molekulargewicht

    91 kDa

    Gen-ID

    22920

    NCBI Accession

    NM_014970, NP_055785

    UniProt

    Q92845
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