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Junctional Adhesion Molecule 2 (JAM2) (Middle Region) Peptid

JAM2 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN978687

Kurzübersicht für Junctional Adhesion Molecule 2 (JAM2) (Middle Region) Peptid (ABIN978687)

Target

JAM2 (Junctional Adhesion Molecule 2 (JAM2))

Spezies

Human

Quelle

  • 4
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Sequenz

    LVAPAVPSCE VPSSALSGTV VELRCQDKEG NPAPEYTWFK DGIRLLENPR

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-JAM2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    JAM2 (Junctional Adhesion Molecule 2 (JAM2))

    Hintergrund

    Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs.

    Alias Symbols: C21orf43, CD322, JAM-B, JAMB, PRO245, VE-JAM, VEJAM

    Protein Size: 298

    Molekulargewicht

    31 kDa

    Gen-ID

    58494

    NCBI Accession

    NM_021219, NP_067042

    UniProt

    P57087
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