Interferon Regulatory Factor 3 (IRF3) Peptid
IRF3
Reaktivität: Human
Wirt: Synthetic
BP, WB
Kurzübersicht für Interferon Regulatory Factor 3 (IRF3) Peptid (ABIN978601)
Target
IRF3
(Interferon Regulatory Factor 3 (IRF3))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
-
-
Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-IRF3 antibody (Catalog #: ARP38061_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Aufreinigung
- Purified
-
-
-
-
Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Konzentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handhabung
- Avoid repeated freeze-thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- IRF3 (Interferon Regulatory Factor 3 (IRF3))
-
Hintergrund
-
IRF3 is interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes.IRF3 encodes interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes.
Protein Interaction Partner: CDKL2,CREBBP,CXCL10,E6,IRF3,CREBBP,EP300,GRIP1,IKBKE,IRF3,IRF5,IRF7,MAVS,PIAS4,PPIB,PRDX1,RELA,SERPINB2,SMURF2,SYT1,TBK1,TICAM1,TICAM2,CREBBP,DDX58,IKBKE,IRF5,IRF7,PPIP5K1,PRDX1,TANK,TBK1
Protein Size: 427 -
Molekulargewicht
- 47 kDa
-
Gen-ID
- 3661
-
NCBI Accession
- NM_001571, NP_001562
-
UniProt
- Q14653
Target
-
Sie sind hier:
