Interferon Regulatory Factor 3 (IRF3) Peptid
IRF3
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle IRF3 Produkte
- IRF3 (Interferon Regulatory Factor 3 (IRF3))
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-IRF3 antibody (Catalog #: ARP31992_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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-
- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- IRF3 (Interferon Regulatory Factor 3 (IRF3))
- Hintergrund
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IRF3 is interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes.IRF3 encodes interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes.IRF3 encodes interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes.
Protein Interaction Partner: CDKL2,CREBBP,CXCL10,E6,IRF3,CREBBP,EP300,GRIP1,IKBKE,IRF3,IRF5,IRF7,MAVS,PIAS4,PPIB,PRDX1,RELA,SERPINB2,SMURF2,SYT1,TBK1,TICAM1,TICAM2,CREBBP,DDX58,IKBKE,IRF5,IRF7,PPIP5K1,PRDX1,TANK,TBK1
Protein Size: 427 - Molekulargewicht
- 47 kDa
- Gen-ID
- 3661
- NCBI Accession
- NM_001571, NP_001562
- UniProt
- Q14653
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