Iron-Responsive Element Binding Protein 2 (IREB2) Peptid
IREB2
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle IREB2 Produkte
- IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-IREB2 antibody (Catalog #: ARP40509_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))
- Hintergrund
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IREB2 binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. IREB2 binds to the IRE element in ferritin which results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
Alias Symbols: ACO3, FLJ23381, IRP2, IRP2AD
Protein Interaction Partner: YBX1,YBX1,YBX1
Protein Size: 963 - Molekulargewicht
- 105 kDa
- Gen-ID
- 3658
- NCBI Accession
- NM_004136, NP_004127
- UniProt
- P48200
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