Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (C-Term) Peptid
IRAK4
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN978590
150,78 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach:
Deutschland
Lieferung in 15 bis 22 Werktagen
Kurzübersicht für Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (C-Term) Peptid (ABIN978590)
Target
IRAK4
(Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequenz
- TGLPAVDEHR EPQLLLDIKE EIEDEEKTIE DYIDKKMNDA DSTSVEAMYS
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-IRAK4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))
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Hintergrund
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This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: IPD1, NY-REN-64, REN64, IRAK-4
Protein Interaction Partner: PELI2,IRAK1,MYD88,PELI1,PELI2,TBPL1,TICAM2,TRAF6,IRAK1,MYD88,PELI1,PELI2,PELI3,TIRAP,TRAF6,UBC
Protein Size: 336 -
Molekulargewicht
- 36 kDa
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Gen-ID
- 51135
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NCBI Accession
- NM_001145256, NP_001138728
Target
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