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Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (C-Term) Peptid

IRAK4 Reaktivität: Human Wirt: Synthetic BP, WB

Produktnummer ABIN978590

Kurzübersicht für Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (C-Term) Peptid (ABIN978590)

Target

IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))

Spezies

Human

Quelle

Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)

Protein Region

C-Term

Sequenz

TGLPAVDEHR EPQLLLDIKE EIEDEEKTIE DYIDKKMNDA DSTSVEAMYS

Produktmerkmale

This is a synthetic peptide designed for use in combination with anti-IRAK4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

Aufreinigung

Purified
Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (N-Term) peptide
IRAK4 Wirt: Synthetic BP, Imm

Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (N-Term) peptide
IRAK4 Reaktivität: Human Wirt: Synthetic BP, WB

Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (C-Term) peptide
IRAK4 Reaktivität: Human BP Sodium azide

Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (N-Term) peptide
IRAK4 Reaktivität: Human, Maus Wirt: Synthetic BP, BI

Applikationshinweise

Each Investigator should determine their own optimal working dilution for specific applications.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Lyophilized

Rekonstitution

Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

Konzentration

1 mg/mL

Buffer

Final peptide concentration is 1 mg/mL in PBS.

Handhabung

Avoid repeated freeze-thaw cycles.

Lagerung

-20 °C

Informationen zur Lagerung

For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target

IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))

Hintergrund

This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: IPD1, NY-REN-64, REN64, IRAK-4

Protein Interaction Partner: PELI2,IRAK1,MYD88,PELI1,PELI2,TBPL1,TICAM2,TRAF6,IRAK1,MYD88,PELI1,PELI2,PELI3,TIRAP,TRAF6,UBC

Protein Size: 336

Molekulargewicht

36 kDa

Gen-ID

51135

NCBI Accession

NM_001145256, NP_001138728

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