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Integrator Complex Subunit 6 (INTS6) (C-Term) Peptid

INTS6 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN978577
  • Target Alle INTS6 Produkte
    INTS6 (Integrator Complex Subunit 6 (INTS6))
    Protein Region
    C-Term
    Spezies
    Human
    Quelle
    • 1
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-INTS6 antibody (Catalog #: ARP36404_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    INTS6 (Integrator Complex Subunit 6 (INTS6))
    Hintergrund
    DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. INTS6 is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and located in the critical region of loss of heterozygosity (LOH). DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and located in the critical region of loss of heterozygosity (LOH). Three transcript variants encoding two different isoforms have been found for this gene.

    Alias Symbols: DBI-1, DDX26, DDX26A, DICE1, DKFZP434B105, HDB, INT6, Notchl2

    Protein Size: 874
    Molekulargewicht
    99 kDa
    Gen-ID
    26512
    NCBI Accession
    NM_001039937, NP_001035026
    UniProt
    A8MV98
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