Inhibin, beta A (INHBA) (N-Term) Peptid
INHBA
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle INHBA Produkte
- INHBA (Inhibin, beta A (INHBA))
- Protein Region
- N-Term
- Spezies
- Human
-
Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- CPSCALAALP KDVPNSQPEM VEAVKKHILN MLHLKKRPDV TQPVPKAALL
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-INHBA Antibody(ARP54663_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
-
-
- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- INHBA (Inhibin, beta A (INHBA))
- Hintergrund
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The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.
Alias Symbols: EDF, FRP
Protein Interaction Partner: INHBA,ACVR1,ACVR1B,ACVR2A,ACVR2B,CHRDL2,ENG,FST,FSTL3,IGFBP7,INHA,INHBA,INHBB,INHBC,TGFBR3,ACVR1B,ACVR2A,ACVR2B,CHRDL2
Protein Size: 426 - Molekulargewicht
- 44 kDa
- Gen-ID
- 3624
- NCBI Accession
- NM_002192, NP_002183
- UniProt
- P08476
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