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Interleukin 27 (IL27) (C-Term) Peptid

IL27 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN978502
150,78 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach: Deutschland
Lieferung in 15 bis 22 Werktagen

Kurzübersicht für Interleukin 27 (IL27) (C-Term) Peptid (ABIN978502)

Target

IL-27 (IL27) (Interleukin 27 (IL27))

Spezies

Human

Quelle

  • 1
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Sequenz

    AQVSWPQLLS TYRLLHSLEL VLSRAVRELL LLSKAGHSVW PLGFPTLSPQ

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-IL27 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    IL-27 (IL27) (Interleukin 27 (IL27))

    Hintergrund

    The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).

    Alias Symbols: IL-27, IL-27A, IL27p28, IL30, MGC71873, p28, IL27A

    Protein Interaction Partner: IL27RA

    Protein Size: 243

    Molekulargewicht

    27 kDa

    Gen-ID

    246778

    NCBI Accession

    NM_145659, NP_663634

    UniProt

    Q8NEV9
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