Iduronate 2-Sulfatase (IDS) (N-Term) Peptid
IDS
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN978399
Kurzübersicht für Iduronate 2-Sulfatase (IDS) (N-Term) Peptid (ABIN978399)
Target
IDS
(Iduronate 2-Sulfatase (IDS))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequenz
- SFPPYHPSSE KYENTKTCRG PDGELHANLL CPVDVLDVPE GTLPDKQSTE
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-IDS Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- IDS (Iduronate 2-Sulfatase (IDS))
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Hintergrund
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Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence similarity with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described.
Alias Symbols: MPS2, SIDS
Protein Size: 550 -
Molekulargewicht
- 59 kDa
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Gen-ID
- 3423
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NCBI Accession
- NM_000202, NP_000193
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UniProt
- P22304
Target
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