Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A) Peptid
IDH3A
Reaktivität: Human
Wirt: Synthetic
BP, WB, IHC
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- Target Alle IDH3A Produkte
- IDH3A (Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A))
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-IDH3A antibody (Catalog #: ARP42237_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- IDH3A (Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A))
- Synonyme
- idh3a Peptide, MGC76128 Peptide, IDH3A Peptide, zgc:56380 Peptide, zgc:85631 Peptide, BG1 Peptide, 1110003P10Rik Peptide, 1500012E04Rik Peptide, AA407078 Peptide, AI316514 Peptide, isocitrate dehydrogenase 3 (NAD+) alpha Peptide, isocitrate dehydrogenase 3 (NAD(+)) alpha Peptide, isocitrate dehydrogenase 3 (NAD+) alpha S homeolog Peptide, idh3a Peptide, IDH3A Peptide, idh3a.S Peptide, Idh3a Peptide
- Hintergrund
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Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. IDH3A is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.
Protein Interaction Partner: IDH3B,IDH3G,SUMO4,DMWD
Protein Size: 366 - Molekulargewicht
- 40 kDa
- Gen-ID
- 3419
- NCBI Accession
- NM_005530, NP_005521
- UniProt
- P50213
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