Isoleucyl-tRNA Synthetase (IARS) (Middle Region) Peptid
IARS
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN978371
150,78 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach:
Deutschland
Lieferung in 15 bis 22 Werktagen
Kurzübersicht für Isoleucyl-tRNA Synthetase (IARS) (Middle Region) Peptid (ABIN978371)
Target
IARS
(Isoleucyl-tRNA Synthetase (IARS))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- YEAAKVFGLR SRKLKLFLNE TQTQEITEDI PVKTLNMKTV YVSVLPTTAD
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-IARS Antibody(ARP54954_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- IARS (Isoleucyl-tRNA Synthetase (IARS))
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Hintergrund
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Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Two alternatively spliced variants have been isolated that represent alternate 5' UTRs.
Alias Symbols: FLJ20736, IARS1, ILRS, PRO0785, IRS, ILERS
Protein Interaction Partner: AR,EPRS,GARS,AIMP2,AKTIP,BCAR3,EPRS,GARS,GSTK1,MAGED1,MCC,SGK1,SNCA,TRAF6,TSC22D1,USP19,VHL
Protein Size: 1262 -
Molekulargewicht
- 144 kDa
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Gen-ID
- 3376
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NCBI Accession
- NM_013417, NP_038203
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UniProt
- P41252
Target
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