Heat Shock 70kDa Protein 8 (HSPA8) (N-Term) Peptid
HSPA8
Reaktivität: Human
Wirt: Synthetic
BP, WB, IHC
Produktnummer ABIN978309
Kurzübersicht für Heat Shock 70kDa Protein 8 (HSPA8) (N-Term) Peptid (ABIN978309)
Target
Hsc70 (HSPA8)
(Heat Shock 70kDa Protein 8 (HSPA8))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein Region
- N-Term
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-HSPA8 antibody (Catalog #: ARP48445_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Hsc70 (HSPA8) (Heat Shock 70kDa Protein 8 (HSPA8))
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Hintergrund
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HSPA8 belongs to the heat shock protein 70 family which contains both heat-inducible and constitutively expressed members. The latter are called heat-shock cognate proteins. HSPA8 is a heat-shock cognate protein. The protein binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Two alternatively spliced variants have been characterized to date.The product encoded by this gene belongs to the heat shock protein 70 family which contains both heat-inducible and constitutively expressed members. The latter are called heat-shock cognate proteins. This gene encodes a heat-shock cognate protein. This protein binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Two alternatively spliced variants have been characterized to date.
Alias Symbols: HSC54, HSC70, HSC71, HSP71, HSP73, HSPA10, LAP1, MGC131511, MGC29929, NIP71
Protein Interaction Partner: DNAJB1,STUB1,ABI1,ALDOB,APOB,BAG1,BAG2,BAG3,BAT3,C4orf14,CCT3,CD40,CITED1,CLTA,COL7A1,CXCR4,CYCS,DNAJA1,DNAJA3,DPP3,DYNLL1,ERH,FBP1,GAK,GCH1,GOT2,HDAC3,HSF1,HSP90AA1,HSPA1A,HSPA8,HSPBP1,HSPH1,JAK2,MAPT,PHC1,PPID,RAF1,RB1,REL,RGS2,SP1,STMN1,STUB1,SUMO4,TADA3,TCERG1,TM4SF1,TSSK6,UBB,UCHL1,YWHAG,YWHAQ,BAG1,BAG2,BAG3,BAG4,BRCA1,C4orf14,CDC5L,CFTR,CITED1,CYCS,DNAJA1,DNAJA3,DNAJB1,DNAJC2,DNAJC3,ERH,FANCC,FBP1,GOT2,GPN1,GPR37,HCFC1,HDAC3,HGS,HNRNPD,HSF1,HSP90AA1,HSPBP1,JAK2,MAPT,P2rx7,PACSIN1,PACSIN2,PACSIN3,PARK2,POLR3D,PPID,PPP1CA,PPP1R12B,PPP1R15A,RBX1,RGS2,RPAP1,RUVBL1,STMN1,STUB1,TADA3,TCERG1,TCP1,TM4SF1,TNFRSF1A,TP53,TP53,TP53,UBC
Protein Size: 646 -
Molekulargewicht
- 71 kDa
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Gen-ID
- 3312
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NCBI Accession
- NM_006597, NP_006588
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UniProt
- P11142
Target
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