Homeobox A5 (HOXA5) (C-Term) Peptid
HOXA5
Reaktivität: Human
Wirt: Synthetic
BP, IHC, WB
Produktnummer ABIN978155
Kurzübersicht für Homeobox A5 (HOXA5) (C-Term) Peptid (ABIN978155)
Target
HOXA5
(Homeobox A5 (HOXA5))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Protein Region
- C-Term
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-HOXA5 antibody (Catalog #: ARP39383_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HOXA5 (Homeobox A5 (HOXA5))
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Hintergrund
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In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA5 is a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of the gene encoding HOXA5 may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis.In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HOX1, HOX1.3, HOX1C, MGC9376
Protein Interaction Partner: TWIST1,CDX4,FOXA2,FOXO1,MEIS1,PBX1,TWIST1,FOXA2,FOXO1
Protein Size: 270 -
Molekulargewicht
- 30 kDa
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Gen-ID
- 3202
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NCBI Accession
- NM_019102, NP_061975
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UniProt
- A2D5Y4
Target
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