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Heterogeneous Nuclear Ribonucleoprotein D-Like (HNRPDL) (C-Term) Peptid

HNRPDL Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN978108
  • Target Alle HNRPDL Produkte
    HNRPDL (Heterogeneous Nuclear Ribonucleoprotein D-Like (HNRPDL))
    Protein Region
    C-Term
    Spezies
    Human
    Quelle
    • 9
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-HNRPDL antibody (Catalog #: ARP40586_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    HNRPDL (Heterogeneous Nuclear Ribonucleoprotein D-Like (HNRPDL))
    Hintergrund
    HNRPDL belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. HNRPDL has two RRM domains that bind to RNAs. Two alternatively spliced transcript variants have been described for this gene. One of the variants is probably not translated because the transcript is a candidate for nonsense-mediated mRNA decay. The protein is similar to its family member HNRPD.

    Alias Symbols: HNRNP, JKTBP, JKTBP2, laAUF1, HNRPDL

    Protein Interaction Partner: ATIC,HGS,HNRNPA1,KHDRBS2

    Protein Size: 420
    Molekulargewicht
    46 kDa
    Gen-ID
    9987
    NCBI Accession
    NM_005463, NP_005454
    UniProt
    O14979
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