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Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU) (C-Term) Peptid

HNRNPU Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN978094
150,78 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach: Deutschland
Lieferung in 15 bis 21 Werktagen

Kurzübersicht für Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU) (C-Term) Peptid (ABIN978094)

Target

HNRNPU (Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU))

Spezies

Human

Quelle

  • 3
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Sequenz

    EITYVELQKE EAQKLLEQYK EESKKALPPE KKQNTGSKKS NKNKSGKNQF

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-HNRNPU Antibody(ARP40518_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    HNRNPU (Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU))

    Hintergrund

    HNRNPU belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. HNRNPU contains a RNA binding domain and scaffold-associated region (SAR)-specific bipartite DNA-binding domain. This protein is also thought to be involved in the packaging of hnRNA into large ribonucleoprotein complexes. During apoptosis, this protein is cleaved in a caspase-dependent way. But this cleavage does not affect the function of the encoded protein in RNA metabolism.

    Alias Symbols: HNRPU, SAF-A, U21.1, hnRNP U

    Protein Interaction Partner: ACTB,CR2,ACTB,BTRC,CASP3,CD5,CR2,ELL,EP300,GRIN1,GRIN2D,GTF2H1,NDN,NDRG1,NR3C1,POU3F4,PRMT1,PTPN11,SMN2,SREK1,STAU1,SYK,YAP1,ZNF689,CDK7,CDK9,EP300,GPN1,GTF2F1,HNRNPH1,MAX,MYC,NDN,NR3C1,POLR2A,POLR2J,POU3F4,PRMT1,RUVBL2,SFN

    Protein Size: 825

    Molekulargewicht

    90 kDa

    Gen-ID

    3192

    NCBI Accession

    NM_031844, NP_114032

    UniProt

    Q00839
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