Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (C-Term) Peptid
HNRNPC
Reaktivität: Human, Maus
Wirt: Synthetic
BP, WB
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- Target Alle HNRNPC Produkte
- HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))
- Protein Region
- C-Term
- Spezies
- Human, Maus
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- KMESEAGADD SAEEGDLLDD DDNEDRGDDQ LELKDDEKEP EEGEDDRDSA
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-Hnrnpc Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))
- Hintergrund
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Hnrnpc binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. Hnrnpc may play a role in the early steps of spliceosome assembly and pre-mRNA splicing. Hnrnpc interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules.
Alias Symbols: AL022939, D14Wsu171e, Hnrpc, Hnrpc1, Hnrpc2, hnRNPC1, hnRNPC2, hnrnp-C
Protein Size: 313 - Molekulargewicht
- 34 kDa
- Gen-ID
- 15381
- NCBI Accession
- NM_016884, NP_058580
- UniProt
- Q9Z204
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