Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (C-Term) Peptid
HNRNPC
Reaktivität: Human, Maus
Wirt: Synthetic
BP, WB
Produktnummer ABIN978090
Kurzübersicht für Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (C-Term) Peptid (ABIN978090)
Target
HNRNPC
(Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))
Spezies
Human, Maus
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequenz
- KMESEAGADD SAEEGDLLDD DDNEDRGDDQ LELKDDEKEP EEGEDDRDSA
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-Hnrnpc Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))
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Hintergrund
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Hnrnpc binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. Hnrnpc may play a role in the early steps of spliceosome assembly and pre-mRNA splicing. Hnrnpc interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules.
Alias Symbols: AL022939, D14Wsu171e, Hnrpc, Hnrpc1, Hnrpc2, hnRNPC1, hnRNPC2, hnrnp-C
Protein Size: 313 -
Molekulargewicht
- 34 kDa
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Gen-ID
- 15381
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NCBI Accession
- NM_016884, NP_058580
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UniProt
- Q9Z204
Target
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