Hepatocyte Nuclear Factor 4, alpha (HNF4A) (N-Term) Peptid
HNF4A
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN978082
Kurzübersicht für Hepatocyte Nuclear Factor 4, alpha (HNF4A) (N-Term) Peptid (ABIN978082)
Target
HNF4A
(Hepatocyte Nuclear Factor 4, alpha (HNF4A))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequenz
- MRLSKTLVDM DMADYSAALD PAYTTLEFEN VQVLTMGNDT SPSEGTNLNA
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-HNF4A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Hepatocyte Nuclear Factor 4, alpha (HNF4A) peptide
HNF4A Reaktivität: Human, Schwein, Hund Wirt: Synthetic BP, Imm
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HNF4A (Hepatocyte Nuclear Factor 4, alpha (HNF4A))
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Hintergrund
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The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms.
Alias Symbols: HNF4, HNF4a7, HNF4a8, HNF4a9, HNF4alpha, MODY, MODY1, NR2A1, NR2A21, TCF, TCF14
Protein Interaction Partner: CREBBP,ELP3,H3F3A,SMARCA4,COPS5,CREBBP,ESR1,FOXO1,HNF1A,HNF4A,MAPK14,MECR,MED1,MED14,NCOA1,NCOA2,NCOA6,NPPA,NR0B2,NR2C2,NR2F1,NRBF2,NRIP1,PNRC1,PNRC2,PPARGC1A,PPARGC1B,PRKAA2,PROX1,SIRT1,SMAD2,SMAD3,SMAD4,SP1,SREBF2,SUB1,TP53,TRIM24,UBE2I,ZNHIT3,AR,COPS5,CREBBP,CTNNB1,EXT2,FOXO1,GPS2,HDAC3,HDAC4,HNF4A,MAPK1,MAPK3,MED1,MED10,MED14,MED16,MED17,MED21,MED23,MED24,MED7,NCOA1,NCOA2,NCOA6,NCOR2,NPPA,NR0B2,NR1I3,NR2C2,NRIP1,PABPC4,PCBD1,PNRC1,PNRC2,PPARGC1A,PPARGC1B,PRMT1,PROX1,RAD50,SIRT1,SMAD3,SMAD4,SNCG,SP1,SREBF1,SREBF2,STK16,SUB1,TGS1,TP53,UBE2I,VDR,XPO1,ZNHIT3
Protein Size: 474 -
Molekulargewicht
- 53 kDa
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Gen-ID
- 3172
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NCBI Accession
- NM_000457, NP_000448
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UniProt
- P41235
Target
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