High Mobility Group Box 1 (HMGB1) (N-Term) Peptid
HMGB1
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN978051
Kurzübersicht für High Mobility Group Box 1 (HMGB1) (N-Term) Peptid (ABIN978051)
Target
HMGB1
(High Mobility Group Box 1 (HMGB1))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-HMGB1 antibody (Catalog #: ARP38109_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HMGB1 (High Mobility Group Box 1 (HMGB1))
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Hintergrund
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HMGB1 belongs to the HMGB family. It contains 2 HMG box DNA-binding domains. The protein binds preferentially single-stranded DNA and unwinds double stranded DNA. The oxidized HMGB1 may accumulate even in cells under oxidative stress.
Alias Symbols: DKFZp686A04236, HMG1, HMG3, SBP-1
Protein Interaction Partner: HNRNPK,MECP2,RB1,TP53,TP73,TP73,AES,AGER,AR,ATOH1,C14orf1,C1orf103,CASP3,CEBPB,CRMP1,CSNK1A1,CTCF,CUX1,DNMT1,ERF,FOXA3,FOXC1,HES1,HNRNPK,HOXD9,HR,IRF2,MECP2,MNT,NCAN,NEUROD6,NFKB1,PLAT,PLG,POU5F1,PPP2R3A,PRKCA,PRKDC,RAG1,RASSF4,RB1,RBPJ,RELA,RFX1,SIX5,SOX18,TAF1,TBP,TFE3,TGIF1,TLE1,TLE2,TLR2,TLR4,TP53,TP73,UNC119,ZFP36,AES,AR,C14orf1,C1orf103,CDK1,CRMP1,CSNK1A1,GTF2A1,HNRNPK,HOXB1,HOXB3,HOXC6,HOXD10,HOXD11,HOXD3,HOXD8,HOXD9,MECP2,NCAN,NFKB1,NR3C1,PGR,PLAT,PLG,POU5F1,PTPRZ1,RAG1,RB1,RELA,TBP,TLE1,TP53,TP73,UBC,UNC119
Protein Size: 215 -
Molekulargewicht
- 25 kDa
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Gen-ID
- 3146
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NCBI Accession
- NM_002128, NP_002119
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UniProt
- P09429
Target
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