Hexokinase 1 (HK1) (N-Term) Peptid
HK1
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN978013
Kurzübersicht für Hexokinase 1 (HK1) (N-Term) Peptid (ABIN978013)
Target
Hexokinase 1 (HK1)
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequenz
- CQQSKIDEAI LITWTKRFKA SGVEGADVVK LLNKAIKKRG DYDANIVAVV
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-HK1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Hexokinase 1 (HK1)
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Hintergrund
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Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus, the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein.
Alias Symbols: HK1-ta, HK1-tb, HK1-tc, HKI, HXK1
Protein Interaction Partner: ENO2,SCMH1,VDAC1,VDAC2,C12orf44,ENO2,GBAS
Protein Size: 921 -
Molekulargewicht
- 103 kDa
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Gen-ID
- 3098
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NCBI Accession
- NM_033498, NP_277033
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UniProt
- P19367
Target
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