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Histone Cluster 1, H3a (HIST1H3A) (N-Term) Peptid

HIST1H3A Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN978007
  • Target Alle HIST1H3A Produkte
    HIST1H3A (Histone Cluster 1, H3a (HIST1H3A))
    Protein Region
    N-Term
    Spezies
    Human
    Quelle
    • 1
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    KQTARKSTGG KAPRKQLATK AARKSAPATG GVKKPHRYRP GTVALREIRR
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-HIST1H3A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    HIST1H3A (Histone Cluster 1, H3a (HIST1H3A))
    Hintergrund
    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

    Alias Symbols: H3/A, H3FA, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J

    Protein Interaction Partner: AURKB,CBX1,RAD51L1,SETDB1,SUV39H1,UHRF1,ALL1,ANP32A,ASF1A,ASF1B,ASH1L,ASH2L,AT3G49660,ATRX,AURKB,BAZ1B,BPTF,CALCOCO1,CARM1,CBX1,CBX3,CBX5,CBX7,CDYL,CHAF1A,CHAF1B,CHD1,CHD3,CREBBP,CTCFL,CUL4A,DDB1,DEK,DNMT3A,DYRK1A,EED,EGLN1,EHMT1,EHMT2,EID1,EP300,ERCC6,EZ

    Protein Size: 136
    Molekulargewicht
    15 kDa
    Gen-ID
    8350
    NCBI Accession
    NM_003529, NP_003520
    UniProt
    P68431
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