Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) Peptid
Kurzübersicht für Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) Peptid (ABIN977988)
Target
Spezies
Quelle
Applikation
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-HIF3A antibody (Catalog #: ARP39936_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))
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Hintergrund
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HIF3A is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression.The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. At least three transcript variants encoding three different isoforms have been found for this gene.
Alias Symbols: IPAS, MOP7, PASD7, HIF-3A, bHLHe17
Protein Interaction Partner: EGLN1,EGLN2,EGLN3,HIF1A,VHL
Protein Size: 667 -
Molekulargewicht
- 72 kDa
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Gen-ID
- 64344
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NCBI Accession
- NM_152794, NP_690007
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UniProt
- Q9Y2N7
Target
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