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Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) Peptid

HIF3A Reaktivität: Human Wirt: Synthetic BP, IHC, WB
Produktnummer ABIN977988
  • Target Alle HIF3A Produkte
    HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))
    Spezies
    Human
    Quelle
    • 4
    Synthetic
    Applikation
    Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-HIF3A antibody (Catalog #: ARP39936_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))
    Synonyme
    HIF-3A Peptide, IPAS Peptide, MOP7 Peptide, PASD7 Peptide, bHLHe17 Peptide, Ipas Peptide, NEPAS Peptide, Mop7 Peptide, HIF3A Peptide, hypoxia inducible factor 3 alpha subunit Peptide, hypoxia inducible factor 3, alpha subunit Peptide, HIF3A Peptide, Hif3a Peptide
    Hintergrund
    HIF3A is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression.The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. At least three transcript variants encoding three different isoforms have been found for this gene.

    Alias Symbols: IPAS, MOP7, PASD7, HIF-3A, bHLHe17

    Protein Interaction Partner: EGLN1,EGLN2,EGLN3,HIF1A,VHL

    Protein Size: 667
    Molekulargewicht
    72 kDa
    Gen-ID
    64344
    NCBI Accession
    NM_152794, NP_690007
    UniProt
    Q9Y2N7
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