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Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) Peptid

HIF3A Reaktivität: Human Wirt: Synthetic BP, IHC, WB
Produktnummer ABIN977988

Kurzübersicht für Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) Peptid (ABIN977988)

Target

HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))

Spezies

Human

Quelle

  • 4
Synthetic

Applikation

Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
  • Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-HIF3A antibody (Catalog #: ARP39936_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))

    Hintergrund

    HIF3A is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression.The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. At least three transcript variants encoding three different isoforms have been found for this gene.

    Alias Symbols: IPAS, MOP7, PASD7, HIF-3A, bHLHe17

    Protein Interaction Partner: EGLN1,EGLN2,EGLN3,HIF1A,VHL

    Protein Size: 667

    Molekulargewicht

    72 kDa

    Gen-ID

    64344

    NCBI Accession

    NM_152794, NP_690007

    UniProt

    Q9Y2N7
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