Histone Deacetylase 6 (HDAC6) (C-Term) Peptid
HDAC6
Reaktivität: Human, Maus
Wirt: Synthetic
BP, WB, ChIP
Produktnummer ABIN977910
Kurzübersicht für Histone Deacetylase 6 (HDAC6) (C-Term) Peptid (ABIN977910)
Target
HDAC6
(Histone Deacetylase 6 (HDAC6))
Spezies
Human, Maus
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
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Protein Region
- C-Term
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Sequenz
- VCHHEASEHP LVLSCVDLST WCYVCQAYVH HEDLQDVKNA AHQNKFGEDM
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-Hdac6 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HDAC6 (Histone Deacetylase 6 (HDAC6))
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Hintergrund
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Hdac6 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Hdac6 plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.
Alias Symbols: Hd6, Hdac5, Sfc6, mHDA2
Protein Size: 1149 -
Molekulargewicht
- 126 kDa
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Gen-ID
- 15185
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NCBI Accession
- NM_010413, NP_034543
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UniProt
- Q9Z2V5
Target
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