Blocking Peptide (BP), Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
Produktmerkmale
This is a synthetic peptide designed for use in combination with anti-HDAC6 antibody (Catalog #: ARP31451_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
HDAC6
(Histone Deacetylase 6 (HDAC6))
Hintergrund
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.
Alias Symbols: HD6, JM21
Protein Interaction Partner: BCL3,BCL3,BCOR,BRMS1,EP300,HDAC11,PLAA,RELB,RUNX2,SIRT2,TUBA1B,TUBA4A,TUBB,UBB,UBB,VCP,ZBTB16,BCOR,CBFA2T3,DNAJB6,DNAJB8,EEA1,EGFR,EP300,HDAC11,RELB,RUNX2,UBC,UBE2D1,UBE2D3,UBE2E1,UBE2H,ZBTB16