H2A Histone Family, Member Y2 (H2AFY2) (Middle Region) Peptid
H2AFY2
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN977826
150,78 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach:
Deutschland
Lieferung in 15 bis 22 Werktagen
Kurzübersicht für H2A Histone Family, Member Y2 (H2AFY2) (Middle Region) Peptid (ABIN977826)
Target
H2AFY2
(H2A Histone Family, Member Y2 (H2AFY2))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- PRIHPELLAK KRGTKGKSET ILSPPPEKRG RKATSGKKGG KKSKAAKPRT
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-H2AFY2 Antibody(ARP57281_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- H2AFY2 (H2A Histone Family, Member Y2 (H2AFY2))
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Hintergrund
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H2AFY2 is the variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. H2AFY2 may be involved in stable X chromosome inactivation.
Alias Symbols: macroH2A2
Protein Interaction Partner: tat
Protein Size: 372 -
Molekulargewicht
- 40 kDa
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Gen-ID
- 55506
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NCBI Accession
- NM_018649, NP_061119
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UniProt
- Q9P0M6
Target
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