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H1 Histone Family, Member O, Oocyte-Specific (H1FOO) (Middle Region) Peptid

H1FOO Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN977820

Kurzübersicht für H1 Histone Family, Member O, Oocyte-Specific (H1FOO) (Middle Region) Peptid (ABIN977820)

Target

H1FOO (H1 Histone Family, Member O, Oocyte-Specific (H1FOO))

Spezies

Human

Quelle

  • 3
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Sequenz

    KAPKAGQGPN TKAAAPAKGS GSKVVPAHLS RKTEAPKGPR KAGLPIKASS

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-H1FOO Antibody(ARP53205_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    H1FOO (H1 Histone Family, Member O, Oocyte-Specific (H1FOO))

    Hintergrund

    H1FOO may play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. H1FOO is essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling.

    Alias Symbols: MGC50807, osH1

    Protein Size: 346

    Molekulargewicht

    36 kDa

    Gen-ID

    132243

    NCBI Accession

    NM_153833, NP_722575

    UniProt

    Q8IZA3
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