This is a synthetic peptide designed for use in combination with anti-GTF2B antibody (Catalog #: P100989_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
GTF2B
(General Transcription Factor IIB (GTF2B))
Hintergrund
GTF2B is the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II.This gene encodes the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: TF2B, TFIIB
Protein Interaction Partner: BAX,EP300,POU3F2,THRA,UL48,VDR,BCL3,CREBBP,DHX9,EP300,ESR1,ESRRA,FOXF2,GTF2B,GTF2E1,GTF2E2,GTF2F1,GTF2F2,HSF1,IKZF1,JUN,MCM2,NCOA1,NCOA3,NCOA4,NOLC1,NR2F1,NR5A1,POLR2A,POU3F2,PSMC2,PSMC5,REL,RELA,TAF9,TBP,TBPL1,TCEA2,THRA,TRAM2,VDR,ATF4,BCL3,CREBBP,CTBP1,CTDP1,DHX9,FOXF2,GTF2E1,GTF2E2,GTF2F1,GTF2F2,GTF2H4,HSF1,HSF1,IKZF1,JUN,KLF5,MECP2,MED21,MYC,NCOA1,NCOA4,NR2F1,NR5A1,PKP2,POLR2A,POLR2H,POLR2J,POLR3A,PSMC2,REL,RELA,TAF11,TBP,TBPL1,TCEA1