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Gastrin-Releasing Peptide (GRP) (C-Term) Peptid

GRP Reaktivität: Human Wirt: Synthetic WB, BP
Produktnummer ABIN977703

Kurzübersicht für Gastrin-Releasing Peptide (GRP) (C-Term) Peptid (ABIN977703)

Target

Gastrin-Releasing Peptide (GRP)

Spezies

Human

Quelle

  • 20
Synthetic

Applikation

Western Blotting (WB), Blocking Peptide (BP)
  • Protein Region

    C-Term

    Sequenz

    ENRNHQPPQP KALGNQQPSW DSEDSSNFKD VGSKGKGSQR EGRNPQLNQQ

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-GRP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    Gastrin-Releasing Peptide (GRP)

    Hintergrund

    This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. Its preproprotein, following cleavage of a signal peptide, is further processed to produce either the 27 aa gastrin-releasing peptide or the 10 aa neuromedin C. These smaller peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants encoding different isoforms.

    Alias Symbols: BN, GRP-10, preproGRP, proGRP

    Protein Interaction Partner: DPP4,GRPR,MEP1A,MEP1B

    Protein Size: 141

    Molekulargewicht

    15 kDa

    Gen-ID

    2922

    NCBI Accession

    NM_001012512, NP_001012530
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