Glutamate Receptor 1 (GLUR1) (N-Term) Peptid
GLUR1
Reaktivität: Maus
Wirt: Synthetic
BP, WB
Produktnummer ABIN977672
Kurzübersicht für Glutamate Receptor 1 (GLUR1) (N-Term) Peptid (ABIN977672)
Target
Glutamate Receptor 1 (GLUR1)
Spezies
Maus
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequenz
- CGALHVCFIT PSFPVDTSNQ FVLQLRPELQ EALISIIDHY KWQTFVYIYD
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-Gria1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Glutamate Receptor 1 (GLUR1)
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Hintergrund
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Gria1 is an ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
Alias Symbols: 2900051M01Rik, AI853806, Glr-1, Glr1, GluR-A, GluRA, Glur-1, Glur1, HIPA1, GluA1, gluR-K1
Protein Size: 907 -
Molekulargewicht
- 99 kDa
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Gen-ID
- 14799
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NCBI Accession
- NM_001113325, NP_001106796
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UniProt
- P23818
Target
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