GRB2-Related Adaptor Protein (GRAP) (Middle Region) Peptid
GRAP
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle GRAP Produkte
- GRAP (GRB2-Related Adaptor Protein (GRAP))
- Protein Region
- Middle Region
- Spezies
- Human
-
Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- KRQIFLRDEE PLLKSPGACF AQAQFDFSAQ DPSQLSFRRG DIIEVLERPD
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-GRAP Antibody(ARP52210_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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GRB2-Related Adaptor Protein (GRAP) peptide
GRAP Reaktivität: Human, Ratte, Rind (Kuh), Maus Wirt: Synthetic BP, Imm
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- GRAP (GRB2-Related Adaptor Protein (GRAP))
- Hintergrund
-
This gene encodes a member of the GRB2/Sem5/Drk family. This member functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain.
Alias Symbols: MGC64880
Protein Interaction Partner: ARHGAP32,ARHGAP32,EPOR,FASLG,FYN,KHDRBS1,KIT,LAT,LCK,PLCG1,SHC1,SOS1,EPOR,FASLG,GAB2,KIT,LAT,SOS1
Protein Size: 217 - Molekulargewicht
- 25 kDa
- Gen-ID
- 10750
- NCBI Accession
- NM_006613, NP_006604
- UniProt
- Q13588
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