GRB2-Related Adaptor Protein (GRAP) (Middle Region) Peptid
GRAP
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN977661
Kurzübersicht für GRB2-Related Adaptor Protein (GRAP) (Middle Region) Peptid (ABIN977661)
Target
GRAP
(GRB2-Related Adaptor Protein (GRAP))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- KRQIFLRDEE PLLKSPGACF AQAQFDFSAQ DPSQLSFRRG DIIEVLERPD
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-GRAP Antibody(ARP52210_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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GRB2-Related Adaptor Protein (GRAP) peptide
GRAP Reaktivität: Human, Ratte, Rind (Kuh), Maus Wirt: Synthetic BP, Imm
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- GRAP (GRB2-Related Adaptor Protein (GRAP))
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Hintergrund
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This gene encodes a member of the GRB2/Sem5/Drk family. This member functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain.
Alias Symbols: MGC64880
Protein Interaction Partner: ARHGAP32,ARHGAP32,EPOR,FASLG,FYN,KHDRBS1,KIT,LAT,LCK,PLCG1,SHC1,SOS1,EPOR,FASLG,GAB2,KIT,LAT,SOS1
Protein Size: 217 -
Molekulargewicht
- 25 kDa
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Gen-ID
- 10750
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NCBI Accession
- NM_006613, NP_006604
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UniProt
- Q13588
Target
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