Glucose-6-Phosphate Isomerase (GPI) (C-Term) Peptid
GPI
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN977590
Kurzübersicht für Glucose-6-Phosphate Isomerase (GPI) (C-Term) Peptid (ABIN977590)
Target
GPI
(Glucose-6-Phosphate Isomerase (GPI))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequenz
- SFDQWGVELG KQLAKKIEPE LDGSAQVTSH DASTNGLINF IKQQREARVQ
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-GPI Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- GPI (Glucose-6-Phosphate Isomerase (GPI))
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Substanzklasse
- Viral Protein
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Hintergrund
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This gene belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.
Alias Symbols: AMF, GNPI, NLK, PGI, PHI, SA36, SA-36
Protein Interaction Partner: AMFR,CSNK2A1,GPI,IGFBP3,PARP14,UBC
Protein Size: 558 -
Molekulargewicht
- 63 kDa
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Gen-ID
- 2821
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NCBI Accession
- NM_000175, NP_000166
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UniProt
- P06744
Target
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